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@gingerw

@zukertort70 Welcome to Mayo Clinic Connect. Have you discussed this with your endocrinologist, yet? Is the proteinuria a result of diabetes? If it is not, you may very well want to find the root cause of that before moving forward.

Is this drop in eGFR a one time thing, or a trend? That is how we look at changes in our kidney function. Dehydration can be a big cause of changes, as can time of day the labwork is pulled, different machines processing samples, exercise just before labs, etc.
Ginger

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Replies to "@zukertort70 Welcome to Mayo Clinic Connect. Have you discussed this with your endocrinologist, yet? Is the..."

It is a trend thing. Three years ago my GFR was 85 but now it has reached 75. Basically, gradually but steadily my creatinin level is rising, for example nine months ago it was 1.10 but now it is 1.21. I suffer from IGA nephropathy according to biopsy with my current protein 24 hour urine at 1500 mgdl. I was prescribed prednisone for six months which brought down my proteinuria to 800 mgdl but raised other minerals in my blood. I have been on ramipril as well for six months but my protein 24 hour still vacilates between 1200-1500 mgdl and now my nephrologist has put me on Farxiga for three weeks and I am non-diabetic. However, I feel all these medications are doing more harm to my kidneys than good and I am considering giving them up completely and resort to herbs and fish oil instead.