I passed on taking Leflunomide after reading it can take 2 years to leave your body. To me that meant if you have problems on it, , it could take an awfully long time to feel better. Had you previously tried other drugs? I’m on prednisone and methotrexate results. Tried to taper off prednisone and had to go back on it. Will do a much slower taper this time. Definitely a no fun at all roller coaster.