This graph showed the distribution of CTX values among postmenopausal women who were treatment naive (never had any meds for osteoporosis) in TRIO study. Basically it shows that for most untreated postmenopausal women with op, CTx falls in "normal range"; only about 20% had baseline CTX above the upper boundary of the normal range while very few below 250.

Was your set of bone markers (ctx 321, p1np 49) done recently near the end of tymlos treatment? Did you have bone markers done during tymlos therapy? What is your plan after tymlos? Thanks!