← Return to Bone turnover markers (CTX and P1NP): do you have a baseline?

Discussion

Bone turnover markers (CTX and P1NP): do you have a baseline?

Osteoporosis & Bone Health | Last Active: 2 days ago | Replies (197)
Comment receiving replies
@rajmayo22

How do you interpret this slide?

I am about to complete my 2 yrs of Tymlos. My basic metabolic panel #s are normal. Mt CTX is 321 and P1NP is 49. Unfortunately, I don't have baseline value from Aug 2022 as I or my Endo wasn't familiar with OP markers like CTX and P1NP. Endo, however, did thorough blood work and urine test for routine markers. We waited to start Tymlos until my Calcium, and VitD returned to normal range.

Thanks

Jump to this post

Replies to "How do you interpret this slide? I am about to complete my 2 yrs of Tymlos...."
mayblin | @mayblin | Aug 2, 2024

This graph showed the distribution of CTX values among postmenopausal women who were treatment naive (never had any meds for osteoporosis) in TRIO study. Basically it shows that for most untreated postmenopausal women with op, CTx falls in "normal range"; only about 20% had baseline CTX above the upper boundary of the normal range while very few below 250.

Was your set of bone markers (ctx 321, p1np 49) done recently near the end of tymlos treatment? Did you have bone markers done during tymlos therapy? What is your plan after tymlos? Thanks!

VIEW AND REPLY