I have a condition called CVID. Common Variable Immunodepression or Boy in the Bubble disease. Not as bad, but I don't make antibodies to viruses or bacteria so I give myself blood plasma of IgG gammaglobulin of other peoples antibodies. So the latest gastro news for people like me is not to take probiotics. I also have low IgA which messes with your gut. I happen to be taking a very small amount of Lyrica for another condition and it seems to be slowing down things so might be a blessing. I also stopped drinking the protein drink I had been drinking every morning with lots of added "stuff" in it and switched to Truvani protein powder which is really clean and tastes good and that doesn't give me a bloated feeling after drinking. This has been a thirty year fight.