Hello @mnewland99
I have about 3 weeks left in the first cycle. I am doing the “doublet” RMC 9805 and RMC 6236. After chemo wash out my marker rose to 233. I’ll find out late today where it stands now after a month of these drugs. Side effects are an annoying rash and diarrhea/constipation. The latter being part of our life anyway-right?
Results of this trial for those with KRAS G12D seem very positive. Tumor shrinkage and less or no progression. Probably not a cure, but a break from toxic chemo.
My markers went from normal to a slow ride as yours. I knew I was becoming resistant even though scans weren’t showing it; so I began looking in February. My April scan showed 1 possibly two tumors as suspected. These allowed me into the trial.
You are smart to be thinking ahead. We all must be doing that. Fortunately, there are back up plans