I am not using this product, nor is my spouse, but I do read up on it: low dose naltrexone
we are talking ultra low doses of a generic compound, not the Naltrexone doses for OD or the levels used for alcoholics
it works miracles in some, and not at all in others
you may have to find a compounding pharmacy and of course, a physician willing to listen and learn
https://ldnresearchtrust.org/
My spouse has progressive degenerative disc disease plus the plasma/bone marrow syndrome of IgM MGUS with worsening peripheral neuropathy in feet and legs
His dose of percocet was 20mg per day the past 12 yrs, pain management doc dropped to 10, which has been unbearable and is back at 15 --still in chronic pain, with chronic insomnia.
also on 20 mg of valium per day x 12 yrs; recently upped to 30; no perceptable improvement

trying to get a full neuropsych eval to see if there are other mechanisms (he's done all the PT, acupuncture, injections --which make everything worse for 48- 72 hours or longer, etc) had 2 surgeries in cervical vertebrae, and is facing more damage now in thoracic vertebrae and bone spurs recurring that impinge on esophagus and trachea

I suspect much of his cycle of pain is uninterrupted and if he would attempt yoga, biofeedback, meditation it might help, it might do nothing, but it would not hurt

he isn't amenable to that "touchy feely" stuff and it makes life a struggle
we used to live near and use a major medical center/research institution for medical care
then he wanted to retire to a country/rural setting and thought life would be simpler
it is simply more challenging, no great medical specialists in the region, an hour in the car to a dr appointment is torture (in his mind) and rural medicine on the whole is an underfunded and ignored need/specialty of its own in the US
also, he has limited options for primary care and I am unimpressed with their intellectual curiosity to see and manage a complex patient
at 66 his mindset is that his life is over

he is sedentary, his diet is poor in nutritional quality (I prepare healthy meals, he ignores fruits and vegetables) and drinks diet soda all day/night long
I think his numbers suggest he's pre-diabetic (I was a lab scientist on the research side) and not one dr has followed up
his heme-onc has NPs see him for follow-up and they seem to lack a depth of knowledge and he gets frustrated, angry and doesn't listen well
so I try to go to all his appointments, and take notes and follow up through patient portal when the inevitable Q arise that he did not ask in the appointment