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@westernflyer

Can only comment on my experience. Mine was localized; Gleason 3+3; T1 as slow-growing prostate cancer diagnosed after two (2) biopsies. The first question is how much the cancer has spread. If the cancer is well-defined and in a specific localized within the prostate, then the option for proton radiation therapy might be an option. I went through 2.5 months of proton radiation therapy at Loma Linda Hospital in 2010.

If the cancer is throughout the prostate gland, then other more radical options are available to include surgery.

The question from what I understand from my experience and reading volumes on the issue is the "intensity" or the scale of cancer. PSA is the "marker" usually, but not always, but usually so. The steps to validate the locations and intensity would be perhaps the PET scan followed by a biopsy. Then the options for radiation, surgery, or other are considered. THIS IS JUST MY VIEW-ALWAYS OBTAIN A SECOND OPINION OR MORE.

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Replies to "Can only comment on my experience. Mine was localized; Gleason 3+3; T1 as slow-growing prostate cancer..."

I'm curious did you ask for a 2nd Opinion on your 2nd Biopsy Pathology Slides . ?
My 1st Biopsy was negative -- My 2nd Positive Gleason 3 + 3 = 6 in six cores . I am awaiting the results of a 2nd opinion on the 2nd Biopsy results to assure me they did not miss any Gleason 7 or more likely misdiagnose the six Gleason 6 --- some being 7 .

As I previously reported my 1st Biopsy came back negative . My 2nd Biopsy 6 cores out of 16 were Gleason 3 + 3 = 6 .
The 2nd Opinion of my Gleason 6 slides just came back , not G6 , but all Gleason 7 .
What next : A 3rd Opinion of my 2nd Biopsy pathology results . -- Put them all in a hat and draw one out -- Just joking . But which one do you believe ?