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Options for unresectable tumor with SMV involvement

Pancreatic Cancer | Last Active: Aug 17 3:34pm | Replies (16)

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@mnewland99

Hi gamaryanne- how is your clinical trial going? What is the name of it? I’m considering it. Ive been on a chemo vacation for 2 weeks and my ca19-9 went from 19 to 91, so not happy about the results. The CT I had just days before the vacay showed nothing new and in fact shrinkage of the existing liver lesions. I hope it’s going well for you.

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Replies to "Hi gamaryanne- how is your clinical trial going? What is the name of it? I’m considering..."

Hello @mnewland99
I have about 3 weeks left in the first cycle. I am doing the “doublet” RMC 9805 and RMC 6236. After chemo wash out my marker rose to 233. I’ll find out late today where it stands now after a month of these drugs. Side effects are an annoying rash and diarrhea/constipation. The latter being part of our life anyway-right?
Results of this trial for those with KRAS G12D seem very positive. Tumor shrinkage and less or no progression. Probably not a cure, but a break from toxic chemo.
My markers went from normal to a slow ride as yours. I knew I was becoming resistant even though scans weren’t showing it; so I began looking in February. My April scan showed 1 possibly two tumors as suspected. These allowed me into the trial.
You are smart to be thinking ahead. We all must be doing that. Fortunately, there are back up plans