@elmay - I had a very rare form of autoimmune GI disease - found that out after years of testing. I started with a known illness- collagenous colitis.With treatment it appeared to go away, but I was feeling miserable most of the time for several years. Biopsies would show random patches of inflammation on and off and in different places. Usually improved on Prednisone and somewhat on Budesonide. Then finally there was an answer - I had severe GI reaction to chemo many years ago- now that was recognized as a trigger for this autoimmune illness. Other conditions that could lead to this are abdominal trauma and gunshot wounds to the abdomen. I then requested to be treated with Imuran - a recommended immunosuppressive. It worked, but side effects of severe infections.