Wow I have been trying to find out if someone else was doing this. Yes it works perfectly for me, maybe for different reasons than you. My problem was if I took it in the morning as prescribed by my doctor by the time I woke up the next morning my muscles and joints were very sore and stiff. They would ease up as the morning progressed and since I would take my prednisone around 9am I was pretty good by early afternoon. I also tried split dosage in am and pm, this worked better than the am only dosage but I still would wake up with manageable degrees of aches and pain. Bottom line was that taking the full dosage at night around 8pm works perfectly for me from a pain management perspective. Hope this helps.