I know it seems like sidestepping the question, but there are so many behavioral variations that predicting the exact nature of the disease progression is impossible. We may categorize the cases according to some published or word of mouth information, but planning for the future is very challenging. We need to keep communicating and trying new strategies, but ultimately, it's a guessing game. Paradoxes and ironies are plentiful, while we caregivers keep trying to figure things out. Sometimes it just plain feels like a losing battle, sad to say.