← Return to Breast cancer treatment and osteoporosis

Discussion

Breast cancer treatment and osteoporosis

Breast Cancer | Last Active: Oct 23 2:09pm | Replies (78)
Comment receiving replies
@donnakatherine

Hi Brighterdays,

I've been chasing this idea around Google Scholar as I consider taking a bone drug and which one. One doctor has recommended Fosamax. Another doctor has recommended Zometa.

A 2024 meta-analysis indicates that breast cancer survival benefits accrue differently to different diagnoses and menopausal status and are small in all cases. This supersedes earlier research, which showed greater recurrence benefits; they discuss why that might be the case.

They also discuss that there is no "standard" standard of care for the adjuvant use of bisphosphonates in breast cancer treatment. It's the wild west.

Here's a link to the article (I found the Discussion and Conclusion sections helpful).
https://www.cell.com/heliyon/fulltext/S2405-8440(24)00824-7
Also, you might find additional helpful articles in the citations.

Jump to this post

Replies to "Hi Brighterdays, I've been chasing this idea around Google Scholar as I consider taking a bone..."
donnakatherine | @donnakatherine | Jul 26 1:04pm

A 2015 study published in The Lancet said this:

"The effect on distant recurrence was mainly because of a reduction in bone recurrence (10-year risk 7·8% vs 9·0%; RR 0·83, 95% CI 0·73–0·94; 2p=0·004; figure 1)."

Whether or not that's still supported, I don't know.

Here's a link: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)60908-4/fulltext.

It's mentioned early in the study that Heliyon published (link above).

VIEW AND REPLY