I have been dealing with non-diabetic neuropathy for 20 years. In the last 4 years or so, I’ve pretty aggressively tried many supplements and prescription drugs.

My results:

Lyrica helps more than anything else. Benfotiamine helps some and Alpha-Lipoic 700 mg from Nuturna (not cheap so I switched to Benfotiamine, one of its main ingredients) has been very helpful.

Lion’s Mane did nothing, acetyl l-carnitine did nothing, NAC did nothing.

The above were all recommended by people, all were mentioned on this forum.

That said, some things work for some people and not for others.

Non-drug therapy:

I have begun spinal decompression therapy with my chiropractor. It is not at all painful and after the first 2 weeks with 5 visits a week, my lower legs have feeling, I can step into a shower and feel the temperature on my feet for the first time in 20 years and I have feeling in the bottom of my feet for the first time in 20 years. Some foot tingling is still there which I hope will go away with continued decompression. I began the decompression not knowing if insurance would pay any of it but it has become clear that it is something that works extremely well for me and may help me stop my drug therapy. This doesn’t mean that it will work for you or work this quickly. My chiropractor tells me that what has changed for me in two weeks usually takes about a year. I’m extremely happy with how things are progressing and will stick with it to try to eliminate all tingling. To be continued.