Tabrecta has caused me mainly fatigue & swelling. I also have arthritis pain & fibromyalgia & I think the tabrecta makes it worse. The Dr. will not reduce my dosage. I have started using Air Compression boots for circulation & this does help the swelling. Do you also have mucinous adenocarcinoma? They told me it looks like pneumonia on x-ray & said it was rare. The Dr. said it had been in my lungs for two to six years. They had been treating me for bronchitis & pneumonia before they took a biopsy (wedge) & decided it was lung cancer.