The doctor determines. This is a discussion you need to have with your doctor and the infusion team. There are different protocals. We can't answer. I can tell you at UC Health they do a standard protocol one year apart. But now I am going to something different because I am on the Tymlos for two years. You don't do them together. There might be other protocals. You can also call the pharmaceutical company who makes the medication and ask them about various protocols. Good luck!

It was just how it worked out with my schedule. The Reclast actually works for more than a year, but is less effective as time progresses. It was good enough for me that I'm now at osteopenia stage. I lift a lot of weights and walk/garden/woodwork, take Ca and Mg, and all the other stuff we are supposed to do. Everyone is different regarding needs and meds.