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Do people with an ileostomy metabolize medication differently?

Posted by g13 @g13, Jan 20, 2022

If we metabolize foods differently, don't we metabolize
medicines differently? I know that what I eat, passes through
my body within a few hours, I've been told that I should not be prescribed a slow-release medicine because of the speed of it passing through the body. So my question is, shouldn't the mg of the medicine be adjusted up to compensate for the speed of the foods and meds passing so quickly?

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g13 | @g13 | Jul 18 2:35pm
In reply to @steve1k "IM works best if you are trained to give injections, this way the medication does not..." + (show)
@steve1k

IM works best if you are trained to give injections, this way the medication does not go through the intestines. If you have Crohn's with an ileostomy, the large intestine absorbs anything ingested. This is why medication dosages may change depending on if the disease is active or in remission. I have taken pills for Crohn's and they were not absorbed. I could tell this as I saw the whole medication in my ileostomy output. Everyone is different. I have lived with Crohn's for 50 years.

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My hole large intestine was removed. Meds don't seem to work.

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harrison221 | @harrison221 | Aug 30 7:49pm
In reply to @catelynn "I am interested to know about the metabolism of meds with an ileostomy? --- Should meds..." + (show)
@catelynn

I am interested to know about the metabolism of meds with an ileostomy? --- Should meds be regulated differently? I am learning to cope with an ileostomy and am happy to discover this Mayo clinic support group!

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I have an ileostomy. You can check with your pharmacist and if possible crush your pills and take them in apple sauce. Also you can use gel caps if possible or liquids.

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kenc | @kenc | Aug 31 2:48pm

Also check to see if the meds your are taking are available in soluble form.

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