I can't speak to taking just R-ALA alone since it was just one of the supplements I am taking for neuropathy. I started taking the protocol regiment in Sept 2016 and didn't start noticing a difference until December of 2016. At that point in time it seemed like my numbness wasn't as bad and hadn't progressed any more. The numbness went from just below the knee down to just above my ankles during the 2 to 3 month time. Then just this past year I seem to have a little more feeling in my feet although they are still numb and tingling. This is really subjective on my part since no additional testing has been done.

This is a complete list of what I am taking.

I think it was actually about a month taking 200mg a day. However I have to say the improvement has waned and walking has become very difficult at about 9 month.i now need a cane. Finally gave in to using one. I can look into increasing ALPA and see if it's an option. After connecting dots I now realize that this Idiopathic Neuropathy started 30 years ago when powerwalking craze my feet slapped the ground and instead i just jogged on me toes.