Connect
← Return to Erleada and Lupron: Does this combo wipe anyone else out?
Discussion
Erleada and Lupron: Does this combo wipe anyone else out?
Prostate Cancer | Last Active: Oct 21 1:27pm | Replies (49)Comment receiving replies
I don't remember your stage, but there's good evidence emerging that "treatment holidays" — stopping ADT and ARSI and waiting to see if your PSA starts rising again — produce overall-survival outcomes that are as good or slightly better for EARLIER STAGE prostate cancer.
Last I read, the evidence still showed slightly worse outcomes after treatment holidays for stage 4, but I'm still hopeful that will change when they've collected more data.
You're the CEO of your treatment team, so after hearing advice, it's your final decision what to do. I opted against a treatment holiday because I'm stage 4b oligometastatic and tolerating the hormone treatment well, but I may change my mind when a the results of a few more studies are in.
Replies to "I don't remember your stage, but there's good evidence emerging that "treatment holidays" — stopping ADT..."
Connect
(I should add that it's not just about fighting the cancer: according to the lengthy drug-manufacturer brochures they give us at the pharmacy, ADT and ARSI can increase the risk of other dangerous conditions like heart disease, obesity/diabetes, and osteoporosis, so even if a treatment holiday slightly increases the risk of your cancer coming back as castrate-resistant, you and your treatment team might decide that's a smaller danger for you, personally, than elevated risk of a heart attack.)