I'm impressed that your rheumatologist said to try different ratios to see what works for you.

I split my dose 2/3 in the morning and 1/3 in the evening when I needed to because of pain in the early morning hours. I agree that the ratio might be different for someone else.

Being unable to sleep at night was a problem for me when I started on 60 mg. When I took all of it in the morning I had to increase my dose to 100 mg. It was just a very high dose but my ophthalmologist said I needed that much. I wasn't able to decrease that dose until my dose was split. Splitting my dose allowed me to decrease my total daily dose.

My rheumatologist was more about a "stable dose" meaning I should take the same total dose every day regardless of whether I split my dose or not. She would get upset when I had to increase my dose and pleaded with me not to do that. Only when my symptoms were stable was I told to decrease my dose.

When I split my dose, I was able to take less Prednisone and I slept better!