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How do you know if your cancer has genetic mutations?

Pancreatic Cancer | Last Active: Sep 23 12:41pm | Replies (34)

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@vannkraken

Not sure if this got answered for you, yet. My wife was recently diagnosed with Stage IV non-operable Pancreatic Cancer and we are awaiting her Tempus tumor analysis results. This is a trial I would look into if you or a loved one have a confirmed KRAS g12d mutation. This is one of the first RAS(ON) inhibitor drugs that is not localized to g12c - the compound is RMC-6236 from Revolution Medicines. The Phase III final protocol is being reviewed by FDA and the company is looking to start enrolling the trial by the end of 2024 - the results in the Phase I/Ib look very promising.

I can't post it because my account is new, but there is a link to the presentation to investors on the proposed Phase III that was just held yesterday, 7/15/24 at the Revolution Medicines website on the "Events & Presentations" tab.

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Replies to "Not sure if this got answered for you, yet. My wife was recently diagnosed with Stage..."

@vannkraken, welcome. I noticed that you wished to post a link with your post. You will be able to add URLs to your posts in a few days. There is a brief period where new members can't post links. We do this to deter spammers and keep the community safe.

Obviously the link you wished to include is not spam. Allow me to post the information for you:
- RMC-6236: Pancreatic Cancer Update to
Support Pivotal Phase 3 Trial https://ir.revmed.com/static-files/eeeb0690-0ef4-44b8-b5fe-8d11d8df3c9a