Constant nausea and vomiting

Posted by katelynlanz @katelynlanz, Jun 24, 2023

46 year old female, constant nausea and vomiting for 8 months. Pt. Has history of polycythemia Vera, cervical cancer ( total hysterectomy), thyroid cancer ( total thyroidectomy), hypertension. Pt. has been hospitalized multiple times over the last 8 months with no answers. Pt. has had multiple CT’s and X-rays of the stomach, as well as stomach emptying study, endoscopy, and many blood tests. Everything is “normal”. Doctors say she is an anomaly and cannot diagnose her. They have ruled out gasteroparesis, stool blockage, spreading of cancer, and food allergies. Pt. cannot keep fluids or food down, has very high and very low blood pressures, has had hallucinations, bloody noses, chest pain (usually with the vomiting), has lost 80lbs in the last 5 months, and has been in pre-renal failure many times due to the dehydration. I know there is plenty I am missing so please please please ask questions and I will answer them to the best or my ability. The Pt. is my mother who I am convinced will die unless i find someone who has seen this sort of thing can before and help find me answers. She cannot just be an anomaly with no answer’s. Someone out there has to have seen this before. Please help me.

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Profile picture for stubeckj70 @stubeckj70

I am a 73 year old woman looking for someone with similar issues: Limb-girdle Muscular Dystrophy withcardiopathy(38 years) and now in congestive heart failure; Gastroparesis due to nerve damage of digestive system. (7 years); Pacemaker x 30 years due to slow pulse rate and now it is 0 and I am 100% paced. Pacemaker replaced 5 timesand in 2018 had cardiac resynchronization and defibrillator placed. Chief compliant: Constant nausea .

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Hello. That sounds terrible. As someone prone to nausea in response to many drugs, and as someone who had pregnancy related “morning” sickness 24 hours a day for months, I have a bit of an inkling of your misery from nausea.

You’ve been through so much… What do your Doctors think is the root cause of your nausea?

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Profile picture for stubeckj70 @stubeckj70

I am a 73 year old woman looking for someone with similar issues: Limb-girdle Muscular Dystrophy withcardiopathy(38 years) and now in congestive heart failure; Gastroparesis due to nerve damage of digestive system. (7 years); Pacemaker x 30 years due to slow pulse rate and now it is 0 and I am 100% paced. Pacemaker replaced 5 timesand in 2018 had cardiac resynchronization and defibrillator placed. Chief compliant: Constant nausea .

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Hello, I had chronic nausea for 4 years after colon surgery. Finally my GI doctor prescribed
Nortriptyline 25MG, I take one capsule at bedtime and it began working very soon.
I hope that this can give you relief.

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Profile picture for salliesallie @salliesallie

Hello, I had chronic nausea for 4 years after colon surgery. Finally my GI doctor prescribed
Nortriptyline 25MG, I take one capsule at bedtime and it began working very soon.
I hope that this can give you relief.

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Thanks for this info. I was given Amitryptoline last year for nausea but it stopped working after around 6-7 months. Maybe the dosage was too little (1 10 mg. Tab at night). The dr. Recently upped the dosage to 20 mg (10 mg. in AM
And 10 mg. In evening). I will discuss dosage and timing with my dr. The thought of something working is exciting. My nausea has been debilitating. I have taken Zofran since summer of 2022 and it has stopped working too. Thanks again.

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Profile picture for stubeckj70 @stubeckj70

I am a 73 year old woman looking for someone with similar issues: Limb-girdle Muscular Dystrophy withcardiopathy(38 years) and now in congestive heart failure; Gastroparesis due to nerve damage of digestive system. (7 years); Pacemaker x 30 years due to slow pulse rate and now it is 0 and I am 100% paced. Pacemaker replaced 5 timesand in 2018 had cardiac resynchronization and defibrillator placed. Chief compliant: Constant nausea .

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I pray that this works for you. I care!

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My daughter had it and had surgery to correct. Happy to given you more info. If you go to the MALS foundation website there are several doctor that treat it successfully with surgery. My daughter had hers done in Tampa fl at Tampa General. Dr Christopher DuCoin. He is an absolute angel.

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Profile picture for stubeckj70 @stubeckj70

I am a 73 year old woman looking for someone with similar issues: Limb-girdle Muscular Dystrophy withcardiopathy(38 years) and now in congestive heart failure; Gastroparesis due to nerve damage of digestive system. (7 years); Pacemaker x 30 years due to slow pulse rate and now it is 0 and I am 100% paced. Pacemaker replaced 5 timesand in 2018 had cardiac resynchronization and defibrillator placed. Chief compliant: Constant nausea .

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Have nausea every day. GI dr has done every test and I have been prescribed many meds that don’t work. Have bought many over counter items that don’t work. This is more than eight months now. Even tried Cbd and thc gummies. No help. Is there anyone who can help??

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Profile picture for charles826 @charles826

Have nausea every day. GI dr has done every test and I have been prescribed many meds that don’t work. Have bought many over counter items that don’t work. This is more than eight months now. Even tried Cbd and thc gummies. No help. Is there anyone who can help??

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Hello @charles826 and welcome to Mayo Connect. I am sorry to hear that you have not found any relief from chronic nausea. It sounds as though you and your doctor have been working together to find a solution to this problem. We do have a couple of conversations on Connect about chronic nausea. Here's a link:

--Chronic nausea
https://connect.mayoclinic.org/discussion/chronic-nausea-2/
As you do not mention any surgeries of the digestive tract, I'm assuming that you are otherwise healthy. I'm wondering if the nausea is every day, all day, or if it just occurs during certain times of the day? Are there any particular foods/drinks that are triggers for this nausea?

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Profile picture for charles826 @charles826

Have nausea every day. GI dr has done every test and I have been prescribed many meds that don’t work. Have bought many over counter items that don’t work. This is more than eight months now. Even tried Cbd and thc gummies. No help. Is there anyone who can help??

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Hi charles826, YUCKY YUCKY constant nausea is always the worst, especially after trying everything. For many years I would have 1-3 random episodes with no apparent reason, each episode would last about a week. There was little to no vomiting. I was working then, I owned a tax and bookkeeping business, so I couldn't stay at home during tax season. For me I used: during daytime: charcoal (but it needs to be used 1+hrs before or after anything else), ginger(high doses), hint: don't use ginger if vomiting is a probable action, because it Burns really bad coming out. Promethezine(Phenergan), peppermint gum, small pieces of peppermint candy, filtered water (carried my huge mug everywhere), nibbled constantly on dry cereal(fruit filled mini shredded wheat, corn Chex), never get hungry, stay on cool side, breathe thru nose only . Dramamine non-drowsy didn't exist back then. After work/evenings: loose clothing made a big impact for me.Dramamine (the drowsy one, I took dbl dose), take with lots of water, this dissolves extremely quickly and it burns your throat really bad., Phenergan, low dose Valium helps calm your stomach and your brain. A heating pad on stomach. Laying down, vs sitting relieves some pressure. Sip diluted chicken broth. Are you vomiting? Dry heaves? Temperature of the rooms and of your body, is it elevated? Bowels normal? What was the GI testing for? What did the doctor think about it? What happened 8 months ago ? Like move, change in anything you use :household cleaning, toothpaste, shampoo etc anything that has a scent/smell. I've no idea why it took me so long to figure out that my toothpaste was a big problem. Do you have migraines, neck pain, bloated/pain in stomach?
I know I am wordy, but unfortunately, for different reasons and for no reason I have ample experience with nausea from requiring hospitalization to just find out what works for me. I hope you find some relief FAST!!! Shelley

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Profile picture for charles826 @charles826

Have nausea every day. GI dr has done every test and I have been prescribed many meds that don’t work. Have bought many over counter items that don’t work. This is more than eight months now. Even tried Cbd and thc gummies. No help. Is there anyone who can help??

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Have you had weight loss(unplanned)? Blood in the bowel movements?

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Profile picture for charles826 @charles826

Have nausea every day. GI dr has done every test and I have been prescribed many meds that don’t work. Have bought many over counter items that don’t work. This is more than eight months now. Even tried Cbd and thc gummies. No help. Is there anyone who can help??

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Camomile Tea Peppermint Tea and Ginger.

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