Hi John @bigjohnscho, I really don't have any experience with issues taking R-ALA as I started at 1200 mg daily (600 morning and evening) with no stomach problems. I have read that others have had nausea trying to start at the full dose and worked their way up starting with 100 mg twice daily for a week and then increasing the dosage.

You might want to take a look at the step by step instructions on how to use Connect in the Help Center here - https://connect.mayoclinic.org/help-center/. It does a good job of explaining how to reply to members and post comments and more.

Hoping you find some answers.