I started out with casodex 2021.The side effects hard to get used to.Then I was on firmagon and erleada .I would self inject and take 240mg erleada.After my visit to the Mayo my erleada was halved to 120mg.This helped with my lethargy and terrible constipation.Presently I’m on 120mg erleda which I take before bedtime.I get lupron injections every 4 months.I try and take a nap after lunch.I do my morning walk and physio exercises.I’m pretty good until after 5 or so.Then when I settle down to read or watch a little tv or so that’s when ‘rigor mortis’ sets in for the rest of my day.Getting up from the couch starts a cascade of pain.My spine,my legs and neck make it hard to get up and go up the stairs to get ready to sleep.I sleep well and this cycle repeats itself daily.My psa is .02 and I’m happy to be alive.There are and will be new drugs for which we will benefit .Perhaps,one day,there will be a cure.I think optimism is part of that cure.