Metformin for pre diabetic patients?

Posted by naiviv @naiviv, Jul 11 3:55pm

I was diagnosed as a pre diabetic last week with a glucose of 89 and a A1C of 5.7. I have been using the Mediterranean diet for months which made me lose weight but I confessed I was eating very dark chocolate 2-3 times a week. As soon as I saw the A1C I stopped eating sweets at all. My PCP talked to me about Metmorfin which she prescribes to her pre diabetic patients. Not all of them are taking it they are sticking to their diets. Has anyone with pre diabetes being mentioned Metmorfin and if you are taking it how is it going? I don’t like pills. She wants to do labs in 4 months to see how stopping high carbs, sugar is changing my A1C, but I am doing this for awhile. Let me know. Thank you. Vivian N

Interested in more discussions like this? Go to the Diabetes & Endocrine System Support Group.

With regard to monitoring blood glucose, strips are fine but continuous glucose monitors are available. They can be spendy if purchased out of pocket but many manufacturers have a program for a free or discounted trial monitor. You will need a prescription from your doctor. Unfortunately many insurance providers will not cover CGMs unless you are on insulin so the free trial is a good way to get a couple of weeks worth of monitoring for free and it will give you a very clear understanding of your body’s response to different types of food you eat. I think these monitors run $75 for a monitor that is good for two weeks. Seeing the daily pattern of glucose fluctuations is so very informative and worth it if you have the money to put towards it.

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@tbraibish

As you can see from the comments, everyone’s experience with diabetes will likely be different. I was pre diabetic and was recommended Metformin after my numbers began to creep up. After a bit of half-assing my nutrition I choose to take the Metformin: my endocrinologist (I had thyroid cancer) and PCP expressed its safety and general lack of side effects. Within a month or so of taking Metformin I began to feel tingling in my hands and feet. Way too soon to be experiencing neuropathy!… turns out some people have a negative reaction to Merformin and it results in your B12 levels plummeting- mine were essentially non existent. B12 is crucial to neurological activity. My PCP recommended intensely high doses of B12 (it is one of the vitamins your body will pass any excess amount that it doesn’t need). I choose to be super diligent with my diet and choose a keto diet and intermittent fasting (daily intermittent fasting with monthly multi-day fasts). It is a different eating routine, but it is manageable, I developed great body composition, and was able to manage my diabetes with nutrition and other lifestyle choices. However, I am now fully type 2 diabetic following a surgery to remove a tumor from my small intestine (cancer no.2 😖) which also removed a large part of my pancreas. I am now on insulin to manage my glucose levels.

I share my experiences for three reasons- 1) be aware of the potential side effects and cross interactions of any prescriptions or supplements you are taking. Do your own research and do not rely solely on your doctor; 2) generally speaking, pre-diabetes can be managed with diet choices and fitness. It doesn’t have to be extreme but it does have to be consistent; and 3) despite your efforts, you might progress into full blown diabetes: this does not mean a failure on your part. there are medical and genetic factors that go well beyond diet and nutrition that can affect your body’s resistance to insulin and there is nothing you can do about these- but consistently focus on everything that you have control over, such as nutrition and lifestyle, and you will have much less dependency on the medical approaches.

Good luck and Godspeed!

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Thank you for comment. I wish you a speedy recovery from the surgery. I am very committed to the Mediterranean diet, no sweets at all , exercise 5-6 days a week walking on the treadmill for 30-45 minutes, drinking lot of water and reducing stress. I will get my labs done in 3 months again to check my A1C which was at 5.7 with a glucose level of 90. The reason my PCP talked me into Metmorfin was because both of my parents had maturity onset diabetes at the age of 80-82 and that was controlled with Metmorfin. Both lived to their late 90’s with no other health issues, only aging.
Stay healthy and safe. Godspeed to you too. Get well soon.

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@cehunt57

Glucometers all require some fiddling with at first. There’s a learning curve. I have used an Accucheck and I currently have a One Touch Verio Flex. Both have been really accurate compared to lab blood sugar checks. Most pharmacies have many options. The meters are pretty inexpensive but the test strips can be pricey. My husband found affordable test strips on Amazon. Your provider or pharmacist could make a recommendation.

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Helpful and encouraging to know this. The Accu check meter I bought a few days ago stopped working after just a few uses.
I called customer service this morning and they'll send me a new meter

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I had HbA1c 5.8 last January and fasting glucose of 98 so like you, prediabetic. But as I was not controlling my diet and had stopped exercising for a while before the test, and being like 25 lb overweight, I decided to try lifestyle measures first before taking any medications. Unfortunately for some family issues I haven't been consistent with lifestyle changes till recently. I did some intermittent fasting and started exercising again, slowly and gradually. I am planning to recheck labs after 3 months of consistent diet and exercise, and if still out of control I may think of taking pills. Like you, my father was diagnosed with diabetes at the age of 70 and still doing well on medications (but not metformin) at 78 now, and several family members were diagnosed with type 2 diabetes.

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I understand that if a person takes thyroid medications and metmorfin is added to the medication regime, the thyroid medication like synthroid could lower the effect of metmorfin. Has anyone being diagnosed with hypothyroidism or hyperthyroidism is taking metmorfin too? Any change in glucose levels?
Thank you.

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Interesting. I’m on both now. Before taking metformin A1C was 6.2 last check 5.9. I have check up in August will mention this to my doctor.

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@doclarrea

I suppose you mean Metformin or glucophage? If so, I take it also for pre diabetes. I have been a pre diabetic for a few years and recently my fasting glucose was 108 and my endocrinologist started me on glucophage 750, which I have been taking every day. Recently I had blood work and my numbers are ok. Had had no side effects from it, so far, I also avoid sugars when I can. I use stevia. However, I do not deprive myself of desert when I want. Also for breakfast I usually drink green juice with fruit and raw oatmeal, and pure 100% honey.

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That is all sugar!!! Try protein for breakfast like eggs.

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Hi,
I agree with you - less meds you take and can get healthy lab results on your own, the better for your health. I know it is sometimes necessary to take meds, but if I have a choice, I opt out.

Couple years ago after lab results, my concierge PCP informed me that because my A1c had been going up over the years, I was now pre-diabetic at 6.2. I was so mad that he had never said a word while every night I was indulging in baked potatoes , huge choc chip cookies, etc. I stopped eating all carbs, sugar, bread, rice, pasta etc. I lost so much weight a friend asked me "Are you dying?"
Around that time, I read about METFORMIN - not the med you mentioned - in an long article in Time magazine or maybe Newsweek, that Metformin was like the "fountain of youth" for your organs. Asked the PCP and he said he was taking it himself for off -label indications such as delayed aging, less cancer risk, etc. Before I began taking, the PCP said to take it and stay near a toilet for at least an hour in case it didnt agree w/ me. Luckily never had any problems and felt it was worth taking the chance. I started taking 500mg Extended Release each night. It didnt immediately make things a lot better but I have never had Alc as high as 6.2 again.

Last bloodwork, Nov 2023, Alc was 5.5 which is NORMAL.
Before I eat anything, I alway check the Carb and Fiber amts. You probably know, if it says 20 carbs and 5 fibers, you can subtract the fibers from the carbs so only 15 carbs.
I now satisfy my sweet tooth by having Dark Chocolate Mocha Almond Kind bars twice a day - 16 carbs and 7 fibers = 9 carbs for each bar and happy to get the 14 fibers; 58% nuts, low on glycemic index, no sugar alcohols added, no genetically engineered ingredients.

Another trick I have, when I eat fruit I always eat some almonds as the fiber in the almonds helps counteract the natural sugar in the fruit. I eat A kiwi everyday w/ the skin for more fiber and I like the crunch. I wash and wipe dry all fruit, even the organic kind.

Last, I often check things I eat or want to eat at Truefood.tech. It is a project 4 scientists whereby 4 scientists studied processed and ultraprocessed foods. "TrueFood is a research project that unveils the degree of processing of all food products.: Each food is given a rating indicating whether it is good for you to eat or not. To find out more about the project & the scientists, two of whom are associated w/ Harvard Medical School. At the website click the 3 tabs at the top to find out everything about it.
I saw above that tbraibish shared problems some people have taking Metformin and also gave excellent suggestions in the last paragraph. Let us know how you are doing please. Carole

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My stomach has been acting up weird since I started Metmorfin. I feel gaseous and bloated sometimes with the urge to have a BM which happens. Also I have lost my appetite which I have never had in my entire life. I have lost 10 pounds so far. Anyone with side effects? I take 500 mg after breakfast following my PCP’s orders.

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