Doesn't mean much. Rheumatologist has to rule out autoimmune diseases. So a referral can be made. I went through that with neuro he checked my ANA was postivr and sent me to Rheumatologist. They did numerous lab work like 30. All normal. Except on other lab for connective tissue disease slightly elevated but not enough to be connective tissue especially since I don't have symptoms of connective tissue. ANA can be positive and mean nothing most people have a positive ANA but positive with autoimmune symptoms and other positive labs would warrant a diagnosis of an autoimmune disease. Also positive ANA is genetic so if your mom is positive most of the time her kids will too. Hope this helps