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STOP! Don't do this if you have osteoporosis
Osteoporosis & Bone Health | Last Active: 2 days ago | Replies (255)Comment receiving replies
@isabelle7 and @cehunt57 Forteo and Prolia are NOT the same at all. Forteo is an anabolic that builds new (quality) bone through the parathyroid pathway.
From Drugs.com: Forteo is a man-made form of parathyroid hormone that exists naturally in the body. Teriparatide increases bone mineral density and bone strength, which may prevent fractures. Forteo is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. Forteo is for use when you have a high risk of bone fracture due to osteoporosis.
Prolia, like bisphosphonates, is an anti-resorptive that builds bone density by reducing bone turnover.
From UpTo Date online: "Denosumab is a fully human monoclonal antibody to the receptor activator of nuclear factor kappa-B ligand (RANKL), an osteoclast differentiating factor. It inhibits osteoclast formation, decreases bone resorption, increases bone mineral density (BMD), and reduces the risk of fracture."
Prolia is different from all the other medications in the intensity of rebound when stopped.
Both need follow-up. Prolia needs follow up with Reclast (preferably) or alendronate.
Prolia and Forteo are entirely different classes of medications. It is better for many of us to do Forteo first. My docs avoid Prolia entirely because of the risks when stopping.
Replies to "@isabelle7 and @cehunt57 Forteo and Prolia are NOT the same at all. Forteo is an anabolic..."
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@windyshores
Oh, Windy, you are so knowledgeable!! I am so glad I asked!!! We have settled on Forteo (starting in a week) and will follow with Reclast. I think you had suggested that and his endocrinologist agrees. I am so thankful we found her!! We had been dealing with a rheumatologist for his PMR and GCA, then osteoporosis from the steroids. It wasn't long before I knew I needed to find another doctor and I learned on here an endocrinologist was the best.
It's been a game-changer. I mentioned some of these drugs to the rheumatologist who wanted to put him on Fosamax (which I didn't think was best, especially after asking about it on here) and she'd not heard of any of the drugs except Fosamax. It's taken us two, maybe three months since she prescribed the Fosamax to finally have our prescription for Forteo. He has to wait one more week then he starts it. Not looking forward to daily injections since he asks me to give them to him. He has a weird aversion to needles after having to give his mom shots for diabetes from the time he was 8 until he went off to college. So I'm giving him his weekly Actemra injections and I'll do the daily Forteo injections as well. (His dad had a condition where his hands shook so he couldn't give the injections.)
I really appreciate you sharing this very insightful information. And I'm glad you told me about Prolia. We'll stay away from that and stick to Forteo and Reclast.