Everyone reacts to chemotherapy differently. There is no one-size-fits-all when I was diagnosed with stage four I did eight rounds of chemo since then I have done another 10 rounds. I am fortunate that the side effects are small. I mostly had side effects from the drugs that they included with the chemo when I was having infusions every two weeks. Now that I am taking oral xeloda I have virtually no side effects. Will put salt and pepper on them. Sometimes a break for a month is beneficial. Everything works but nothing works all the time.