Hi,
I was on Xolair for about 15+ years - it worked great. I started when it first came out and there were no other biologics. However, after such a long time, it stopped working. I was switched to Tespire - to which I got much worse with numerous side effects. Unfortunately, after being hospitalized with asthma, we searched for another biologic which I am doing well with - I am currently on Dupixent every other week. Thankfully, there is not cost and insurance is covering it. I have improved from Tespire. I am a steroid dependent asthmatic, so this is helping, along with other meds for asthma. Good luck. Pam