During my Folfirinox treatments last year, my oncologist put me on both Olanzapine (helps with appetite and fatigue) and Ritalin (helps with fatigue). Also had the Neulasta shot with every treatment to prevent low white blood cell count that can lead to fatigue and infection (neutropenia) as well. All of which helped me greatly to function better during treatment. I stopped both drugs a few months after my last infusion.