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@dadcue

I started atorvastatin about the same time as the three blood pressure medications. When Prednisone was stopped my cholesterol level was getting too low. Atorvastatin was decreased to half of the lowest available dose. My cholesterol level was still getting too low. An endocrinologist said I was very "sensitive" to atorvastatin even though I took it for 10 years at a higher dose while I was on Prednisone.

My rheumatologist wanted to stop atorvastatin altogether because my CK level was increasing. My rheumatologist was concerned about statin induced myopathy.

My cholesterol level rebounded slightly when atorvastatin was completely stopped. I'm now being tried on Zetia (ezetimibe) to see if it will decrease my cholesterol level a little bit but not too much. I didn't think I needed anything for my cholesterol level if I watched what I eat more closely. My endocrinologist thought I should try Zetia anyway. I think it was because I said that I like pizza once in a while.

Supposedly, Zetia works differently and shouldn't lower my cholesterol level too much.

"The most commonly used class of drugs for lowering cholesterol levels, statins, acts by preventing the production of cholesterol by the liver. Zetia has a different mechanism of action and lowers blood cholesterol by reducing the absorption of cholesterol from the intestine. It does not affect the absorption of triglycerides or fat-soluble vitamins."
https://www.medicinenet.com/lipitor_atorvastatin_vs_zetia_ezetimibe/drug-vs.htm#what_are_the_side_effects_of_lipitor_and_zetia

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Replies to "I started atorvastatin about the same time as the three blood pressure medications. When Prednisone was..."

That’s really interesting. I have never heard of cholesterol being too low?? I have cardiologist and a GP appointments next month. I’m going to ask them about these drugs, especially Zetia. I would love to move away from a statin, but I’m sure this has its downside, too. Thanks again for the help!

I have been taking Zetia for awhile. I thought I was having problems with atorvastatin and then pravastatin. I had fingers that would contract and lock, thumb and index finger mostly. When I stopped taking the statin, this problem stopped. Reading about statin side effects made me think the statin was the culprit. Have not had this happen since. I recently started blaming my upper leg aching on the zetia so I have temporarily stopped taking it. I did talk to my pcp about it. The upper leg aching has stopped.
Anyway, here's a short video about statin induced myopathy:
https://m.youtube.com/watch?v=2PEdByp5LyA