The Methotrexate helped me initially. I was at 8 mg prednisone, couldn't go lower, and the MTX made me feel like I no longer had PMR. I tapered down to 5 mg fairly easily. My doctor was pleased with my progress, told me to stay on 5 mg for 6 months. As time went on PMR symptoms increased. I had to strictly limit activity to keep the pain down. After 5 months I had a bad PMR flare. My liver enzymes also stayed elevated while I was on MTX and I had to get off it. I was glad because I also never felt quite right while on it, just kind of foggy. 6 mg is the highest I've had to go since I took MTX so I think it helped long term. A mixed report from me!