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Duloxetine 20mg

Chronic Pain | Last Active: Jul 11 8:06am | Replies (19)

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@carolinlv

I just took my first dose of 20 mg duloxetine and I’m not enjoying the way I feel at all. How long before this one dose wears off? Doc prescribed it to replace gabapentin for neuropathy but I’m sure I won’t make it through the time it takes to start working. Should I decide to move forward (VERY much on the fence), does it contribute to constipation at all? Definitely won’t make it if it does.

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Replies to "I just took my first dose of 20 mg duloxetine and I’m not enjoying the way..."

I use 90 mg of ER duloxetine at bedtime - morning use didn't work at all for me either, but I was so miserable I stuck with my pain doc and figured out what works - we started with 30, then 60, and recently increased to 90 - all at bedtime. The ER (extended release) is much easier to tolerate as it is released slowly into the body.