I was a bit hesitant too but my endo felt imperative I treat osteoporosis that my Letrozole for invasive lobular cancer put me into within 1 year of starting. I am taking oral Fosamax one daily and will have blood work after 6 months to see if being absorbed as I have chrohns. If not I will probably try Reclast but I wanted to start with Fosamax which has fewer side effects.