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What exactly is NED (no evidence of disease)?
Pancreatic Cancer | Last Active: Jul 9 6:43am | Replies (20)Comment receiving replies
Be aware that ATM mutations are being treated in trials by drugs called ATR-inhibitors (not ATM inhibitors). There have been a few.
berzosertib (formerly M6620, VX-970)
ART0380
Elimusertib (BAY-1895344)
Comonsertib
https://aacrjournals.org/cancerdiscovery/article/11/1/80/3075
https://news.vumc.org/2021/09/23/clinical-trial-tests-atr-inhibitor-in-difficult-to-treat-cancers/
Dr. Yap (in this article: https://www.mdanderson.org/newsroom/results-fgfr-inhibitors-parp-atr-inhibitor-combinations.h00-159617856.html ) is a clinical trial-generating machine, with focus on the DDR deficient mutations like ATM.
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Thank you markymark. I will look into these trials and discuss with my dr on Tuesday. I hope you are doing well in your trial; please update us when possible. Also, have you heard of this drug: dostarlimab? My sister’s friend passed this on for me as something I could look into for pancreatic cancer tumors.