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I've been thinking about this for awhile. One of my obgyns who uses hrt herself did tell me that the use will be for the rest of life unless problem(s) arises. Like @teb pointed out, there are periodic tests/exams and labs need to be done to assess ongoing risks vs benefits. As far as the reoccurence of menopause symptoms after cessation of hrt, my hunch is it will be inevitable, but the magnitude of which is questionable. The estrogen receptors are largely downregulated 10-15 years post menopause, even they get upregulated again by HRT, the biological effects of estrogen won't be as robust as when we were young. If you didn't have troublesome vasomotor symptoms last time, I think its unlikely you'd have worse experiences the second time around. But, all these thoughts are just thoughts. In the event when you are off hrt, you'd definitely follow up with a bisphosphonate or better yet, an anabolic.
Replies to "I've been thinking about this for awhile. One of my obgyns who uses hrt herself did..."
"when you are off hrt, you'd definitely follow up with a bisphosphonate or better yet, an anabolic." I suppose that is what is happening now. I stopped bio transdermals at 58 and now at 67 I'm on the Reclast and the Tymlos.
it seems with the new studies and tests its best to leave the door open to restarting - if even - a lower dose transdermal bio HRT....
Unfortunately, in this time we are living in - although I have first-rate doctors at UCSD - they are becoming more and more specialized and there is no "umbrella" or time for anyone to look at my body "globally." They are willing to do all the tests but it's me who figures out what they all mean - and has to remember them in my head!
mayblin, thanks for the response. I would think your assumptions re second time around sound logical.
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Beside the multiple advantages of taking HRT in perimenopause is bone protection sufficient with HRT alone.