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@agb

Yes, but by itself, that 8.1% means nothing, unless you can compare it against the general population. Below is from the CDC. A bit hard to read as it's copied, but the population estimate of diabetes for 2019-2021 is 10.1% of the population aged 45-64 and 6.8% over 65, so without knowing anything else, the Repatha numbers look pretty normal.

And I agree, some people have side effects, others don't.

Characteristic Population Estimates, 2021a
Number in Thousands (95% CI) Incidence Estimates, 2019–2021
Rate per 1,000 (95% CI)
Total 1,211 (1,094–1,328) 5.9 (5.1–6.9)b
Age in years
18–44 305 (241–369) 3.0 (2.1–4.2)b
45–64 633 (550–716) 10.1 (8.2–12.4)b
≥65 273 (222–325) 6.8 (5.1–8.9)b

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Replies to "Yes, but by itself, that 8.1% means nothing, unless you can compare it against the general..."

When side effects are listed you make an informed decision whether the benefit is worth the risk.