Thank you @bnjncrew. I truly appreciate you taking the time to give me this information. I have watched a lot of videos of people who have taken this and most talk about extreme sensitivity to cold anything, neuropathy and nausea. My sister has a well differentiated pancreatic neuroendocrine tumor Grade 3. May I please ask what your husband’s grade was? We had a video with her oncologist and he said that he if my sister didn’t start this chemo she would qualify for comfort care/hospice if she didn’t want treatment because there has been significant growth. All of this is a lot to try and understand. He said that without treatment she would have a range of about 6 months, more like 3-5 months. It was a very hard appointment. 😭