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Is anyone else talking Wegovy for heart disease?
Heart & Blood Health | Last Active: Jul 9 6:32pm | Replies (11)Comment receiving replies
The side effects listed have occurred in users, not every user, but enough to be listed as a side effect. It’s not listed as a rare side effect which would mean that most people don’t get diabetes, but a low percentage have. Like any drug, you may or may not experience the side effects. A Repatha side effect is diabetes. I don’t want to take that chance. I hope you never get diabetes from Repatha, but the fact that you haven’t gotten it yet does not mean you won’t.
“Among the 16,676 patients without diabetes mellitus at baseline, the incidence of new-onset diabetes mellitus during the trial was 8.1 percent in patients …Jun 23, 2018“
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Yes, but by itself, that 8.1% means nothing, unless you can compare it against the general population. Below is from the CDC. A bit hard to read as it's copied, but the population estimate of diabetes for 2019-2021 is 10.1% of the population aged 45-64 and 6.8% over 65, so without knowing anything else, the Repatha numbers look pretty normal.
And I agree, some people have side effects, others don't.
Characteristic Population Estimates, 2021a
Number in Thousands (95% CI) Incidence Estimates, 2019–2021
Rate per 1,000 (95% CI)
Total 1,211 (1,094–1,328) 5.9 (5.1–6.9)b
Age in years
18–44 305 (241–369) 3.0 (2.1–4.2)b
45–64 633 (550–716) 10.1 (8.2–12.4)b
≥65 273 (222–325) 6.8 (5.1–8.9)b