There must have been some research a long time ago that said Celebrex was safe to take with Prednisone. I was told when all the NSAIDs were compared, Celebrex was least likely to cause GI bleeding. I also took Celebrex with Prednisone for at least a year but that was ages ago during my early years with PMR.

I had to discontinue Celebrex and was told it wasn't safe with Prednisone. I think Celebrex was stopped because I started warfarin after a pulmonary embolism. The warfarin increased my risk of a GI bleed exponentially since I was still taking Prednisone. I think "stomach protection" was added to my medication list at the same time. Of course, stomach protection was only supposed to be taken "as needed" instead of all the time. That rule was also changed when warfarin was added to Prednisone.