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Bone turnover markers (CTX and P1NP): do you have a baseline?

Osteoporosis & Bone Health | Last Active: Oct 5 5:35pm | Replies (183)
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@normahorn

If, and that is a big IF, the "ideal value of CTX/P1NP is 10, then a value > 10 would mean more bone is being lost than produced while a value < 10 would mean more bone is being produced than lost. Those of us with values around 4 should have fantastic bones.

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Replies to "If, and that is a big IF, the "ideal value of CTX/P1NP is 10, then a..."
hopefullibrarian | @hopefullibrarian | Jul 4 5:54pm

I see what's causing this confusion. You're looking purely at the value of CTx divided by P1NP, rather than as a ratio. We're comparing apples to oranges. You are absolutely correct that when dividing CTx by P1NP "a value > 10 would mean more bone is being lost than produced while a value < 10 would mean more bone is being produced than lost." That's an interesting way to look at it, and it does work.
I was taking it a step further to represent it as a ratio which is different, and admittedly more complicated. With the ratio, the larger the number in relation to 10, the better the bone turnover.
Mystery solved!
Thank you for sharing this alternative way of looking at it.

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