I haven't ever had a problem with my port. Certainly no infection. It's completely under the skin, so it doesn't interfere with your life at all. You can shower, swim, etc.

I'm on my second port now. I got the first one removed after I finished my first 6 cycles of chemo. I like to sleep on my stomach, and the port was a hard lump that made that unpleasant. I also had a strange episode of breaking out in hives 5 or 6 weeks after finishing chemo, which I associated with the port, although I don't have evidence that it was involved. Getting the port removed felt a bit like tempting fate, but I did like the feeling that my cancer episode was over.

But when my cancer recurred, I got another one put in before restarting chemo. This one's maybe an inch and a half further to the outside on my chest, just inside my bra strap, and it doesn't bother me as much when sleeping on my stomach. A sports bra covers it, although there's a lump. The new scar also shows under fewer shirts.