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Anastrozole - should I take?

Breast Cancer | Last Active: Jul 7 9:19pm | Replies (31)

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@ladyofthelake1

Age 62- I have the similar type breast cancer. 1st time Cancer.
Stage 1b Er&Pr Positive & HER2 negative.left breast lumpectomy, surgery was MAy 29, 24. I have Sentinal node POS, Next Node Negative. Margins are clear though doctor said. I am suppose to go radiation only treatment this July 24.

Surgeon started me on Anastrozole a week prior to surgery. After a few weeks being on it, I had intense pain in my ankles and tops of my feet where veins are. Same on hands and wrists achy. I felt sluggish. I recently switched two nights ago to Letrozole 2.5mg. Will see in a couple weeks if less pain. I also started walking about 20 minutes in the morning every other day. Will add indoor bicycling soon too.

I still have ovaries. Surgeon recommends I should remove them. All CT scan and MRI are good or unremarkable. I am going to take a bone scan next week. Bracha Gene 🧬 Test is negative.

I’m thinking about ordering Haelin 951.

I wanted to do Proton Radiation Therapy but Surgeon said not enough studies for Lymph node positive. They need to have a combo machine of both Types. Jane

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Replies to "Age 62- I have the similar type breast cancer. 1st time Cancer. Stage 1b Er&Pr Positive..."

@trashycat what was your Oncotype score and your actual ER and PR scores?

With letrozole, I found I had to walk 45 minutes for it to help. At 20 minutes I felt worse in terms of pain, and then it cleared and improved if I kept going. My oncologist told me she had heard this from other patients.

Not everyone can walk 45 minutes so with respect to those with limitations.

I was avoiding soy after cancer due to its estrogenic effects, but more recent reports were contradictory. Haelan 951 appears to have similarly contradictory reviews, even warnings (the ones below are a bit old). Maybe you can share why you are considering it. It seems higher doses starting earlier in life are safer. But lots of controversy.
https://quackwatch.org/cases/fdawarning/prod/fda-warning-letters-about-products-2009/haelan/#:~:text=Haelan%20951%20Ingredients
https://csn.cancer.org/discussion/155238/haelan-951
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104637/
"2.2.2 Breast Cancer One of the most important issues concerning the impact of PhyEs in human health is their ability to either increase or reduce the risk of developing breast cancer. The results so far obtained from preclinical studies are still controversial. Daidzein stimulates the growth of breast cancer cells and potentiates estrogen-induced cell proliferation in the uterus (Gaete et al., 2011). However, high concentrations of genistein inhibits the growth of breast cancer cells regardless of their ER status. On the other hand, low concentrations of genistein stimulate ER-positive breast tumors and abrogate tamoxifen-mediated growth inhibition in ER-positive breast cancer. Recent studies also demonstrated non-estrogenic anticancer effect of isoflavones (e.g., reactivation of epigenetically silenced tumor suppressor genes) (Kwon, 2014)."

Why are they recommending you have your ovaries removed?
Thank you!