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What exactly is NED (no evidence of disease)?

Pancreatic Cancer | Last Active: Jul 9 6:43am | Replies (20)

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@mnewland99

You are a model of what can happen with the BRCA gene, but none of this would be possible with the ATM mutation, which I have. After only 6 months of GAC chemo with I believe only the abraxane reduced to 80%, my CA19-9 numbers are starting to slowly climb upwards every 2 weeks and my basic bloodwork (monocytes, lymphocytes, etc.) are starting to go haywire. I’m still on chemo, but hoping to get into a clinical trial now. From everything I’ve read, I don’t see any long-term success yet for those with ATM gene mutation (I also have KRAS12-D and TP53). It would be great if in profile we could put our mutations which would make our input more pertinent to others.

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Replies to "You are a model of what can happen with the BRCA gene, but none of this..."

Hello Marie, I have KRAS G12D and TP53. A bit fearfully, I am starting s trial this week that targets KRAS G12D and another drug that is considered “pan KRAS”. My tumor marker was 136 at last check. The activity we know of is in my liver.

I will let you know how it goes once an assessment is done in 8 weeks. Maybe it will be of help to you!