I have had IBS-D for over 40 years. I have lived with it as I've had good and bad days and weeks. I gave up gluten 13 years ago and that helped. Not dramatically but enough. I am now still a very active 82 year old and in the last year it has gotten much worse. I've lost 6 lbs. in a month, I have been 133 for the last twenty years and everything I eat just goes right through me. I just got the results of my endoscopy, which showed a lot of inflammation. My gastro said except maybe for a lot of acid, everything looked normal. She wants me to try Viberzi but medicare doesn't cover it and it's very expensive. She is ordering an acid blocker.