I am sure there is a trial that came to the conclusion of the various time intervals that doctors prescribe for ADT. For me, I was a classic biochemical recurrence and we went with a 24-month period.

In terms of does ADT kill cancer, the way my team talks with me is that ADT is starving the cancer cells of what it needs to grow. All cells in our body that are alive are trying to divide and keep going. That is why our finger nails and hair grow (visually you can see this) but inside the body the same things are happening. ADT robs the prostate cancer of the fuel it needs, but like your own body, you could fast for 1-day, 2-days, heck you could skip food for a month and you'd still be alive (all you need is water and air). So to truly starve the cancer, you need a healthy amount of time to put that in action. Think of yourself, you could probably go without food for months and enter into starvation mode and your body would be weak very much so. But if you then started to eat food and nutrition, you likely would recover. same goes for the cancer, ADT is trying to starve every last cell until they can't go any further. Hope this makes sense. KTF

This is the heart of the matter for me. I had three months of Eligard then 33 fractions of IMRT. After 6 months of Eligard i insisted on switching to Orgovyx and they added in Abiraterone. I have now been on that combination 2 months and am 2.5 months post radiation. My PSA is now 0.02. The MO wants me on the ADT for at least 11 more months and preferably 17 more months. But in my mind I’m either cured already and am suffering the ADT side effects for nothing, or I’m not cured so let’s stop, see where the cancer is and then move on to chemo or targeted radiation.