@jprust Nausea, vomiting, metallic taste in mouth, can all be signs that there is a crisis. However, not everyone experiences all these symptoms. Last December when I had a crisis, the only indication was nausea. I thought it was my stepson's cooking being too rich for my liking!

A rapid decline in activity or interest in daily life goings-on, shift in focus or desire to engage. I really hope you or his nephrologist can convince him it is time to think about starting dialysis. It has been proven that the higher your eGFR is when you start, the better chances for a steady outcome. I started at 14%.
Ginger