I was on Firmagon for the first 2 1/2 years, then switched to Orgovyx a couple of months ago (it was approved by Health Canada only last fall, and is still very new here).

I have the regular side-effects from low/no testosterone, but they've very tolerable, and I'm living close to a normal life. Recovering from paraplegia seemed like a much-bigger deal than the ADT side-effects, to be honest — going from bed to wheelchair to walker to can to walking again over the first couple of years made me feel like I was getting better every week.

Specific side-effects: hot flushes (the biggie), reduced body hair (not on my scalp), slightly-lower energy levels, lower iron (but not anemic), mild gynecomastia (just wear a loose shirt), and reduced sexual function, and more challenging to maintain weight. I also had mood swings for the first year, but they don't happen any more.