Understand what companies have to report as side effects: anything that a patient says must be reported, without investigating or if the reported symptoms can possibly be related to the tested drug (I've been a patient in drug trials so this is from personal experience). While I'm not in a position to say whether any of the symptoms are true, again, from experience, I'm on Repatha and have none of the above. No symptoms at all other than it stinging for about 30 seconds after the injection. And it's done an amazing job in lowering total cholesterol, LDL, and lipoprotein B for me, in addition to the statin I've been on for more than 20 years.