@rom828 yes your doctor can explain how helpful the aromatase inhibitors are for hormonal cancers like ours. Again I had grade 3 and cancer cells in my lymph vessels and after 5 years letrozole, no chemo, am 9 1/2 years out knock on wood.

I did another test after 5 years- the Breast Cancer Index- that showed high risk but no benefit from further treatment with an AI. They have changed the risk categorization since then. My risk was 5.7% and they found that patients interpreted that "high risk" label with a lot of fear, though it is in reality a pretty low risk and similar to the Oncotype's low risk for me.